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The most frequently reported side effects include gastrointestinal symptoms such as nausea (occurring in more than 1 in 10 patients), diarrhoea, vomiting, constipation, and abdominal pain
Beyond genetics, biomarkers like fasting insulin, HbA1c, inflammatory markers, and metabolic rate provide clinical context for understanding your individual response profile
35,39 Further supporting the involvement of the autonomic nervous system in the positive chronotropic effect of GLP-1 in rodents is the lack of heart rate increases in response to GLP-1 in isolated perfused rat and mouse hearts
For Wharton, having these pills as treatment options is a matter of accessibility
doi: 10.1271/bbb.100453
The risk-benefit balance may be less favourable for people near a normal BMI than for those who are clearly obese
