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Description
Leptin activates ROCK to alter actin dynamics in cardiomyocytes in JAK2/PI3K axis dependent way [141]
[1] [2] Musculoskeletal side effects were not prominently highlighted as primary adverse outcomes in the published Phase 2 data

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This long half-life is a key reason it is studied as a sustained tri-agonist research tool

Retatrutide is commonly referred to online as a peptide, and it is an investigational molecule studied in clinical trials under the development code LY3437943

SPM helped in analyses of RNAseq data
