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Further, experimental data suggest that the pro-survival action of GLP-1RAs may also be mediated by the Akt-dependent stimulation of the mTORC1/S6K1 pathway, the activation of which is dependent upon the IGF-1R, as observed in rodent islet cells (44)

This elevated urinary glucose environment is nutrient-rich for Candida and other fungal species, increasing infection risk in susceptible individuals