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Quick Answer: Low-dose GLP-1 receptor agonists may exert anti-inflammatory effects by reducing pro-inflammatory cytokines and inflammatory markers, though this application remains investigational without FDA approval or established dosing protocols

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doi: 10.1111/j.1748-1716.2009.01971.x 18 HawleySAGadallaAEOlsenGSHardieDG

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In addition to their glycemic effects, DPP-4 inhibitors have the potential to decrease bone resorption, increase bone formation, and reduce the incidence of osteoporosis and fractures

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CLINICAL TRIAL EVIDENCE FOR DUAL GLP-1/GLUCAGON RAs AND TRIPLE AGONISTS IN MASH Survodutide Survodutide, a weekly dual GLP-1/GCG agonist, was assessed in a phase 2 dose-finding trial (NCT04771273) including 293 individuals with histologically confirmed MASH and fibrosis stages F1-F3 [46]

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