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In conjunction with this edition of Ground Truths theres a podcast with Daniel Drucker , the physician-scientist credited as one of the co-discovers of glucagon-like peptide (GLP-1) nearly 3 decades ago.(Sorry that youre getting 2 emails from me today!) He helps explain some of the new findings that Ill be going through here

This evidence creates a sense of urgency because results are already proven

Metabolic conditions : Hyperparathyroidism, gout, inflammatory bowel disease, type 2 diabetes/metabolic syndrome (particularly for uric acid stones due to low urine pH), and certain genetic disorders affecting urinary chemistry increase susceptibility

Together these data suggest that increased postprandial serotonin may contribute to the pathophysiology of PBH and provide a potential therapeutic target

Gastric sleeve surgery (sleeve gastrectomy) permanently reduces the size of the stomach by approximately 7580%, creating a narrow, tube-shaped pouch

The Role of Dosage Escalation (Titration) One reason you might notice a sudden change in when or how side effects start is a change in your dosage
