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patients were only required to remain persistent on treatment

Potenza ()

Optimizing the use of glucagon-like peptide 1 receptor agonists in type 2 diabetes: executive summary

GLP-1-based therapies and resmetirom operate through distinct and potentially complementary mechanisms: while resmetirom exerts direct hepatic effects by activating THR- to enhance mitochondrial function, reduce hepatic lipogenesis, and promote lipid oxidation specifically in hepatocytes, GLP-1 RAs and multi-agonists address the upstream metabolic drivers of MASLD including insulin resistance, obesity, and systemic inflammation

Lawrence A et al

We thank the core imaging facility of Institut Jacques Monod (ImagoSeine facility) for help in image acquisition and processing
