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In time to event analysis, GLP-1RA use was associated with significantly increased hazard of hypersomnolence at both the 1-year and 5-year time points

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BAT has recently been implicated as a potential target of obesity and metabolic disorders, where induction of UCP-1-mediated NEAT thermogenesis may be a potential therapeutic target [63]

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In an extension cohort (BMI 35), those continuing to 104 weeks lost an average of 30.3%