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The Role of GLP-1 Medications in Fatty Liver Disease Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide (Wegovy) and tirzepatide (Mounjaro), were originally developed to manage type 2 diabetes

However, the evidence in humans remains preliminary and inconclusive, and neither EFSA nor the FSA has issued guidance restricting their use on this basis

Recent studies demonstrate that these drugs can lower your A1C by up to 1.5% and help you drop 10% to 15% of your body weight and in some cases, even more

Mahapatra and colleagues (2022) describe unsaturated fatty acids as potent stimulators of GLP-1 release, citing multiple studies investigating the effects of olive oil on GLP-1 secretion

The scientists studied health outcomes of more than 200,000 people who received one of the two different shingles vaccines and found that the recombinant shingles vaccine, Shingrix, reduces dementia by at least 17% more than the older, but now discontinued, live shingles vaccine, Zostavax