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Many patients experience B12 deficiencies due to dietary restrictions, absorption conditions, or underlying health issues leading to symptoms such as fatigue, brain fog, and low energy

This includes the protein known as Amuc_1100, which we here rename as pilus-associated signaling (PAS) protein , the P9 protein encoded by Amuc_1631, the short-chain fatty acids acetate and propionate, and cell envelope components, such as phosphatidylethanolamine and peptidoglycan.