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Within this period, preimplantation genetic diagnosis (PGD) may be performed especially if either partner has a high risk of transmitting a genetic condition to the offspring

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MASLD and metabolic dysfunctionassociated steatohepatitis (MASH), the histologic phenotype of MASLD characterised by liver injury and inflammation in addition to steatosis, is a major public health issue as it increases the risk of liverrelated complications, such as cirrhosis and hepatocellular carcinoma, while also increasing the rates of fatal and nonfatal cardiovascular events, chronic kidney disease, T2D, extrahepatic cancers [1] and severe bacterial and nonbacterial infections [2]

The remodelling of the ECM is a dynamic process that facilitates cancer cell migration and the establishment of a pro-inflammatory milieu that further supports tumour progression (Fig

Both are GLP-1 agonists, which help control appetite and blood sugar, although they may cause side effects like nausea and gastrointestinal discomfort