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Pharmacology & Therapeutics, 155, 49-59

Phase 3 studies specifically targeting NASH as a primary indication are ongoing

NICE advises against initiating gabapentinoids, opioids, paracetamol, NSAIDs, benzodiazepines, corticosteroids, and antipsychotics for chronic primary pain including fibromyalgia

To fully understand the differences in the mechanisms and long-term effects of GLP-1RAs on the retina, a combination of clinical trials and mechanism studies is necessary (85)

45 Preclinical studies suggest that GLP-1 RAs may exert anti-inflammatory and cartilage-protective effects within the joint, 46 but further research is needed to determine whether these translate into structural improvements beyond symptomatic relief

Jazayeri, A
