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TRANSCEND-T2D-1 randomized 537 adults with type 2 diabetes (baseline A1c 7.0 to 9.5 percent, inadequately controlled on diet and exercise alone) to retatrutide 4 mg, 9 mg, 12 mg, or placebo for 40 weeks
Study limitations include potential unmeasured or uncontrolled confounders, biases, and others inherent in EHR-based observational studies
Alcohol Alcohol can be tricky on its own for people with diabetes, but GLP-1 medications add another layer

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