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Pancreatic DPP-4 As well as influencing glucose homeostasis through its more widespread systemic effects, as discussed above, there is some evidence to suggest that DPP-4 may have local actions in the endocrine pancreas

Alcohol intake and its effect on some appetiteregulating hormones in man: Influence of gastroprotection with sucralfate
Front Aging Neurosci (2019) 11:204
In PWA mice, metformin therapy caused very modest metabolic effects (Fig

Furthermore, studies using a peripherally administered exenatide analogue conjugated to vitamin B12, which is sterically hindered from accessing regions protected by the blood brain barrier, improves glucose control in comparable fashion to unmodified exenatide, presumably at the level of the -cell, but does not induce emesis in the house musk shrew ( Suncus murinus) or rats (78, 79)

[DOI] [PubMed] [Google Scholar] 23.Rosendo-Silva D., Matafome P
