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Serious hypersensitivity reactions (e.g., anaphylaxis, angioedema) have been reported in patients treated with semaglutide tablets

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Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP

Semaglutide is a single GLP-1 agonist

Depot effect at the injection site : The fatty acid moiety promotes self-association and interaction with subcutaneous tissue components at the injection site, creating a slow-release depot that contributes to sustained absorption after subcutaneous administration