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Description
Animal studies reported offspring that were smaller than usual when the parent animal was exposed to doses higher than the dose used in humans

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A meta-analysis of 13 randomized placebo-controlled trials with 1183 participants with T1D reported small reductions in BMI, insulin requirements, total and LDL-C, but no differences in A1C, HDL-C, or triglyceride levels

Patients were dosed for 12 weeks and subsequently discontinued for 4 weeks

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At week 52, more participants in the semaglutide group than in the sitagliptin group achieved weight reductions of 3% (34.8% vs