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Benefits can include: Lower blood pressure Lower total cholesterol Better liver health for those with metabolic dysfunctionassociated steatotic liver disease (MASLD) Lower blood sugar and reduced diabetes risk Lower risk of kidney disease Tirzepatide and orforglipron are newer drugs that dont yet have results from long-term cardiovascular health trials

Progesterone contributes endometrial protection, sleep quality, and mood stability

Psychological risks include disordered eating patterns

Gallbladder problems: Like gallstones

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The SYNERGY-NASH trial demonstrated that tirzepatide achieved MASH resolution in 44-62% of patients compared to 10% with placebo