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Participants taking the highest dose of orforglipron (36 mg) experienced a mean weight loss of 7.3 kg , or 7.9%, compared with 1.3 kg or 1.6% in the placebo group

At 12 months, patients receiving exenatide had a mean improvement of 2.7 points, while the control group had a mean decline of 2.2 points, indicating a statistically significant difference of 4.9 points (95% CI, 0.3-9.4

But they measure completely different things

But remember that its important to check with your doctor or another licensed professional before starting any new exercise program, especially if you havent been active recently

DISCUSSION In the combined SUSTAIN 6 and PIONEER 6 population, semaglutide reduced the risk of MACE versus placebo in subjects with T2D at high risk of CV events

Semaglutide, known by brand names such as Wegovy for weight management and Ozempic for type 2 diabetes, functions as a GLP-1 receptor agonist