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Dosing guidelines suggest starting at a dose of 1.5 milligrams and gradually increasing to the maintenance dose (the dose found to be most effective in clinical trials) of 25 mg, depending on how the person responds and how strong side effects are

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Research shows that somewhere between 25% and 40% of the weight lost on these medications comes from lean muscle mass

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No major drug interaction studies have identified contraindications between these therapies

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