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3.1% for placebo (Jastreboff et al., NEJM 2022)

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It will likely take a combination approach targeting multiple aspects of the immune system and beyond to achieve full clinical remission, which is the ultimate goal of immune therapy [31, 119, 120]

When released in response to dietary fat in the small intestine, CCK binds to CCK1 receptors on vagal afferent neurons, initiating a cascade that activates these neurons and transmits signals to the NTS in the brainstem

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