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Many patients achieve A1C reductions of 12 percentage points within the first three months

Titration Design In the Phase 2 trial published in The New England Journal of Medicine , participants started on a low introductory dose (as little as 24 mg weekly) and were titrated upward over the course of several weeks before reaching target doses of 812 mg

Zhang, Y., & Xu, Y

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Because autoimmune diseases vary so much, patients should not treat this study as a one-size-fits-all answer
These interactions can increase or decrease tacrolimus levels, requiring dose changes
