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The impact of peri-operative anti-TNF treatment on anastomosis-related complications in Crohns disease patients

Postgrad Med J 82:130135 Suwanabol PA, Seedial SM, Zhang F, Shi X, Si Y, Liu B, Kent KC (2012) TGF- and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells

**Key Takeaway:** This decision reinforces the importance of evidence-based medicine and highlights the role of regulatory authorities in ensuring that only safe, effective, and scientifically justified medicines are available to patients

What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience

Any of these require immediate stoppage and medical attention

Still in Phase 3 clinical trials, early results show unprecedented weight loss, with some participants losing over 24 percent of body weight