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Cardiovascular Risk Reduction Semaglutide SELECT demonstrated 20% MACE reduction with semaglutide 2.4 mg in 17,604 patients

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It randomised 156 participants with early disease to daily subcutaneous lixisenatide or placebo for 12 months, followed by a 2-month washout

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Indeed, results from clinical studies examining the efficacy of exenatide or liraglutide as monotherapies or in combination with oral antidiabetes medications in patients with T2D have shown that, at concentrations sufficient to reduce HbA1c, no significant differences in the incidence of major [events that resulted in loss of consciousness, seizure, coma or other mental status change consistent with neuroglycopaenia which resolved after administration of glucagon or glucose or events those that required third party assistance because of severe impairment in consciousness or behaviour and had a glucose value of less than 54 mg/dl (3 mmol/l)] or minor [events that had symptoms consistent with hypoglycaemia and glucose values of less than 54 mg/dl (3 mmol/l) prior to treating the episode] hypoglycaemia compared to placebo were observed (Table 1) [15,21,3740]

Speak to your prescriber before attempting keto, especially if you have diabetes, use insulin, take SGLT-2 medication, have kidney disease, are pregnant, breastfeeding or have a history of eating disorders