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NEW ORLEANS Once-daily orforglipron induced greater reductions in HbA1c than dapagliflozin and oral semaglutide for adults with type 2 diabetes, according to findings from the ACHIEVE-2 and ACHIEVE-3 trials

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While generally well-tolerated, GLP-1 RAs can be associated with adverse events, including pancreatitis, acute kidney injury (AKI), gastroparesis, nausea, diarrhea, abdominal pain, and decreased appetite

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