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Although weight loss becomes more prominent with sustained, consistent use at higher (therapeutic doses), some initial Wegovy results and weight loss are still seen in the first month

Screening for personal or family history of medullary thyroid carcinoma and MEN2 is essential, with patient counseling regarding symptoms such as neck mass, dysphagia, hoarseness, or dyspnea that warrant prompt evaluation

TRIUMPH-5: Obesity + Obstructive Sleep Apnea Apnea-hypopnea index endpoint design parallels the SURMOUNT-OSA program for tirzepatide, which secured an OSA indication for Zepbound in late 2024

When approved, most patients receive their prescription within 24 hours

This is a significant advantage for a medication often used in populations where kidney disease is common, such as those with type 2 diabetes

But no mention has been made including, astonishingly, in the upcoming UN meeting on noncommunicable diseaseof GLP-1 drugs, which are easily as important a health intervention as statins, and seem likely to turn out to be the most consequential medical innovation since vaccines