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Neben den selektiven GLP-1-Rezeptor-Agonisten wie Liraglutid und Semaglutid existieren duale Agonisten (Tirzepatid), die zustzlich den GIP-Rezeptor (glukoseabhngiges insulinotropes Polypeptid) adressieren
Furthermore, targeted delivery of exendin-4 to the nucleus of the solitary tract (NTS) similarly diminished both operant responding for sucrose under a progressive ratio schedule and conditioned place preference for food rewards in rats (Richard et al., 2015)

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