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Serious complications after gallbladder surgery are rare

The now-elevated calcium levels promote exocytosis of GLP-1containing vesicles, releasing GLP-1 into the circulation
Probst L, Monnerat S, Vogt D R, Lengsfeld S, Burkard T, Meienberg A, et al

"We allow people to gauge our citizens as much as they want to

Sodium, potassium, and magnesium all get depleted when you lose intestinal fluid
However, the GLP-1R is also involved in adipogenesis in the periphery, which may account for this discrepancy (Challa et al., Glp1r/ mice, animals with deletion of the GLP-1R in vagal afferent/efferent nerves, Phox2b-Cre Glp1r flox/flox , as well as animals with a deletion of the GLP-1R in the CNS, nestin- Cre Glp1r flox/flox , maintain a similar body weight and food intake as control mice on both chow and HFD (Sisley et al., 2014)