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Those treated with an SGLT2i were more than twice as likely to develop a UTI or pyelonephritis than those treated with a GLP-1 RA (RR 2.27 [95% CI 1.12, 4.55] p =0.019)
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Importantly, rates of gastrointestinal adverse events were similar between groups
The recently approved oral semaglutide should be taken with the recommended amount of water in the fasting state
PMID 40886075
