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In particular, tell your provider if you have or have a past history of: Type 1 or type 2 diabetes Thyroid cancer Pancreatitis Kidney disease Diabetic retinopathy Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding

These events were most common early in treatment, especially without ramp-up dosing

The saffron group showed statistically significant differences in body weight compared with placebo, reduced snacking frequency, and improved subjective satiety

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This figure depicts the interconnected signaling pathways linking gut-derived peptides and central neuropeptides to hypothalamic and brainstem circuits controlling appetite, satiety, and behavior

J Clin Pharm Ther (2021) 46(1):99105