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In these trials, the medication was marketed under the brand name Zepbound for obesity and Mounjaro for type 2 diabetes

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Unlike SGLT2 inhibitors or incretin-based therapies, resmetirom is distinguished by its direct effects on hepatic metabolic abnormalities and its disease-modifying potential for liver-related endpoints (Harrison et al., 2024)

Patients experience limb heaviness, reduced mobility, recurrent infections (cellulitis), and significant psychosocial burden

1 Despite the availability of effective treatments, the achievement of BP targets is challenging and presents a significant global health issue

Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice