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"It is concerning that, in some cases, people can simply go online and order these kinds of medications," researchers said.

Greater investment in early-phase innovation and alternative pharmacological targets will be essential to diversify treatment options and address the unmet need for equitable and sustainable obesity management.

Joint discomfort during GLP-1 therapy can stem from rapid weight loss, medication response, or individual metabolic factors

Some compounding pharmacies are using a different form of an active ingredient, semaglutide, that is not approved by the FDA, state regulators say.

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