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NLRP3 inflammasome activation is an important mechanism of cardiac hypertrophy 36,37

The three substances proposed for exclusion: Semaglutide the active ingredient in Ozempic, Wegovy, and Rybelsus Tirzepatide the active ingredient in Mounjaro and Zepbound Liraglutide the active ingredient in Victoza and Saxenda The FDAs stated rationale: with FDA-approved branded products commercially available, there is no clinical need for 503B outsourcing facilities to compound these medications from bulk substances

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