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Ive always liked this story as their target weight loss molecule, Nimacimab , has much improved tolerance in humans and also high efficacy in animal testing

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Abrams SA, Griffin IJ, Hawthorne KM, Ellis KJ

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The reason for excluding all patients with heart failure was due to our inability to determine the presence of congestive heart failure stage IV, which is contraindicated for GLP1 RA use
