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Where Retatrutide Now Sits vs the Competition Cross-trial comparisons have limitations, but the magnitude gaps are large enough to draw conclusions: Retatrutide at 12 mg produces the largest weight loss of any published Phase 3 GLP-1-class compound

doi: 10.4093/dmj.2020.0258

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For rapidly spreading redness, significant swelling, severe pain, or fever at an injection site, seek same-day assessment by contacting NHS 111 or your GP

Retatrutide may also cause more pronounced heart rate increases