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This attenuation of decreased DRA expression by GLP-1-SSM in DSS colitis mice further substantiates the anti-diarrheal effects of GLP-1 nanomedicine (Figure 1)

Clinical trials show that tirzepatide reduces appetite ratings by 4060% in most patients within 24 weeks of starting treatment

doi: 10.1111/dom.14725 Funding information The STEP 1 trial was funded by Novo Nordisk A/S

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A conceptual model of food cue reactivity, Nutrients (2023) Taking a GLP-1

Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and abdominal discomfort, particularly when treatment is first initiated