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It is also worth considering that improved glycaemic control itself can influence skin health

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Contact your clinician promptly if you notice: Severe or persistent abdominal pain Repeated vomiting with inability to keep fluids down Signs of dehydration such as dizziness or very dark urine Symptoms of low blood sugar if you use insulin or sulfonylureas New severe heartburn or worsening swallowing symptoms Safe use is about the right dose, the right pace, and ongoing monitoring

In contrast, a recent large registry cohort study by Ueda et al., which utilized data from nationwide registers in Sweden, Denmark, and Norway, found no difference in the risk of intestinal obstruction when comparing GLP-1RAs to SGLT2 inhibitors among over 300,000 patients [16]