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Description

Freshly prepared fermentation broth samples, fermentation supernatant samples and bacterial suspension samples were orally administered to mice as soon as possible

Assessing OS biomarkers, including ROS levels, total antioxidant capacity (TAC), lipid peroxidation products and DNA fragmentation, is critical for detecting redox imbalances

Although oral therapy with the least toxic of these compounds, glutathione monoethyl ester, did raise erythrocyte and white blood cell glutathione levels in a few affected patients (W Rhead, unpublished results), it also provoked moderate gastrointestinal irritation resulting in vomiting and diarrhea, largely precluding oral therapy with this compound or other related molecules containing free sulfhydryls

These include acute respiratory distress syndrome (ARDS), asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, idiopathic pulmonary fibrosis, chronic bronchitis and various viral and bacterial infections [3]

Timing of the exposure and the difference between maternal vs embryonic perception of the threat can determine the phenotypic outcome for several generations