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One study assessed changes in anticipatory food reward responses in adults with Prader-Willi Syndrome versus healthy controls, but they found no correlation between these changes and levels of fasting ghrelin (van Nieuwpoort et al., 2021)

Across a year and a half of treatment, participants lost an average of 28% of their body weight

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Expect the first 812 weeks to be an adjustment period where some fluctuation is normal and expected

2.4 Delayed Gastric Emptying GLP-1 receptor agonists slow gastric emptying through: Reduced antral contractility Increased pyloric tone Modulation of vagal signalling This prolongs gastric distension, enhances satiety and contributes to reduced meal size

Research characterized how the acyl chain length, linker chemistry, and attachment position influence albumin binding affinity and proteolytic stability in vitro