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While some physicians are prescribing these medications for their approved uses of treating type 2 diabetes, obesity and obstructive sleep apnea, others are frequently making off-label prescriptions

They cannot make medical claims and have not undergone the same rigorous testing as prescription medications

A 2023 study published in the New England Journal of Medicine found that semaglutide produced clinically meaningful weight loss in over 90% of participants, outperforming naltrexone-bupropion combinations by a significant margin

The trial also indicated the drug's potential to achieve results akin to bariatric surgery

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Additionally, it is important to determine how well the new drugs perform in the long run and whether they are safe