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New England Journal of Medicine, 385(6), 503-515. Pratley, R
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Quick Answer: GLP-1 medications may not work as expected due to inadequate dosage, incorrect administration technique, insufficient treatment duration, lifestyle factors, concurrent medications, advanced beta-cell dysfunction, or unrealistic expectations about timeframes and outcomes

The FDA doesnt regulate this kind of prescribing

Lynn FC, Pamir N, Ng EHC, McIntosh CHS, Kieffer TJ, Pederson RA
