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Limitations The major limitations of the studies that are included in this systematic review are the enrollment of healthy subjects and insufficient data in conditions that might affect pharmacokinetics (e.g., kidney dysfunction)

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SSIB cases associated with GLP-1RAs were identified and analyzed through disproportionality analysis using the information component

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One of the largest US health insurers is ending coverage of GLP-1 weight-loss drugs for its employees but will continue covering them for people with type 2 diabetes.