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Regularly track weight, appetite, hunger patterns, and relevant metabolic markers such as HbA1c

However, these symptoms can negatively affect treatment adherence, quality of life, and discontinuation rates, thereby impacting long-term treatment success

Hormonal imbalance that irregular menstrual cycles caused by anovulation

For patients also taking insulin or sulfonylureas, it's important to check blood glucose levels when feeling cold, as hypoglycemia can present with cold, clammy sensations

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