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doi: 10.1055/s-0032-1328878

All GLP-1 receptor agonists and tirzepatide carry a boxed warning for risk of thyroid C-cell tumors and are contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Fiber and hydration If diet alone isnt enough, fiber supplements for anal fissures or hemorrhoids such as psyllium husk, methylcellulose, or polycarbophil are great options

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In the past year, the growth of prescription drug utilization and spending has much to do with the use of GLP-1 agonists to treat diabetes and obesity, along with immunology therapy, and lipid meds, along with specialty medicines now accounting for over half of spending up from 49% in 2018

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