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How GLP-1 Drugs Affect Brain Chemistry and Mood GLP-1 receptors are distributed throughout the central nervous system, particularly in the hypothalamus, ventral tegmental area, and amygdalaregions that regulate appetite, reward processing, and emotional response

doi: 10.1016/j.jff.2016.01.035

Typically, these effects are temporary and diminish as your body adapts

the process in which food exits your stomach and enters into the small intestine
