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Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes

doi: 10.1056/NEJMoa2309000

The cardiovascular risk reduction in high-risk diabetic and obese patients is large

In addition, metformin also lowers blood glucose by enhancing intestinal glucose uptake

GLP-1 RAs, such as Ozempic and Wegovy, are medications that mimic this hormone

There are other important secondary outcomes, including the change in logMAR visual acuity, the development of center-involved diabetic macular edema (CI-DME) and the development of retinopathy, macular edema or vitreous hemorrhage requiring treatment
