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It is estimated that clinical trials evaluating liver-related events in patients with MASLD and compensated or decompensated cirrhosis would require a minimum recruitment of 2,886 patients with at least four years of follow-up and 1,602 patients with at least two years of follow-up, respectively

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Regenerons Phase 2 COURAGE trial echoed these results in humans: combination therapy significantly reduced fat while preserving up to 81% of lean mass loss compared to semaglutide alone

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It supports the fullness signal