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In patients with diabetes mellitus not achieving targets on lifestyle measures, pharmacologic therapy should be considered

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However, due to the slimming properties of the drug, semaglutide is often abused by non-diabetics, non-obese individuals, and young people

Glucagon-like-peptide-1 (GLP1) analogs may induce thyroid or pancreatic diseases in animals, raising questions about their use in diabetic patients

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Phase 3 programmes also evaluated long-term safety, tolerability, and metabolic outcomes, forming the basis for subsequent regulatory approvals in certain jurisdictions