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Description
Nogueiras, R

Glucagon-like peptide 1 secretion by the L-cell: the view from within
The DM control group consisted of patients with T2DM who were prescribed insulin or glucose-lowering drugs but not incretin-based drugs (GLP-1 RAs or DPP-4 inhibitors)

Taken altogether, these findings underscore the growing potential of dual/multi-agonist therapies to target the cardiometabolic phenotype closely linked to HFpEF

The reduction in -cell mass in patients with T2DM can be attributed to -cell apoptosis triggered by multiple factors, including islet amyloid deposition, lipotoxicity, glucotoxicity, and inflammation (You et al., 2022)

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