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Natasha Yates wishes to thank Dr Terri-Lynne South a GP, dietician, and the chair of the Royal Australian College of General Practitioners specific interest group in obesity management for providing feedback and peer review on this article.

Why Results Vary With GLP-1

doi: 10.1056/NEJMoa2302392 53 FriasJPHsiaSEydeSLiuRMaXKonigMet al

Off-label, it's widely used for weight loss due to 5-15% body weight reduction in trials like SUSTAIN

The right choice depends on what you value most

There is no evidence to suggest that tirzepatide should be discontinued solely due to throat discomfort unless directed by your healthcare provider
