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Description
Results indicate that GLP-1RA users, defined as those with a history of use exceeding six months and at least two refills within six months prior to the procedure, had a higher incidence rate of aspiration pneumonia (0.83%) compared to nonusers (0.63%), corresponding to a hazard ratio of 1.33
In Phase 3 TRIUMPH-4, about 20.9% of participants at the highest dose reported dysesthesia, which means unusual skin sensitivity or tingling

doi:10.1136/jim-2021-001952
A weight-loss plateau after initial progress is often metabolic adaptation, not treatment failure
I was also 89 kgoverweight for me

In the isolated perfused rat heart, acute GLP-1R agonism protects from ischemia/reperfusion injury [625,626], an effect that can be blocked by pretreatment with either exendin (939), the cAMP inhibitor Rp-cAMP, the PI3 Kinase inhibitor LY294002 or the MAP Kinase inhibitor UO126 [625]
