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Consequently, a thoughtful riskbenefit analysis becomes central to clinical decision-making

Using a genetically engineered mouse model, the researchers demonstrated that newer small-molecule GLP-1 drugssuch as recently approved oral medicationscan reach deep brain regions

Patients with T2D with stable CAD presented an improvement in endothelial function expressed by an increase in flow-mediated vasodilation of the brachial artery, independent of changes in systolic and diastolic blood pressure during a hyperinsulinemic clamp in response to GLP-1 [35]

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Increased FFA in the liver results in insulin resistance, hepatic glucose production, and pancreatic beta cell dysfunction [7]

The mean age was similar between groups (approximately 3234 years across all subgroups)